The comparison of hypertonic saline (7.5%) and normal saline (0.9%) for initial fluid administration before spinal anesthesia.

Hypertonic 3% Saline in Comparison with 0.9% (Normal) Saline in Treatment of Acute Bronchiolitis

BackgroundBronchiolitis is the commonest cause of lower respiratory tract infection in infant. Respiratory syncytial virus is the commonest cause of bronchiolitis. This study aimed to assess the efficacy of nebulized 3% hypertonic saline and salbutamol in the treatment of acute bronchiolitis in comparison with nebulized 0.9% saline and salbutamol.Materials and MethodsA prospective case second m...

Hypertonic saline prehydration in patients undergoing transurethral resection of the prostate under spinal anaesthesia.

Thirty-three patients undergoing elective transurethral resection of the prostate were allocated randomly to receive either 0.9% isotonic saline 7 ml kg-1 (16 patients), or 3% hypertonic saline 7 ml kg-1 (17 patients) as a preload before spinal anaesthesia. After spinal anaesthesia, the incidence of systolic arterial pressure < 75% of control value was greater in the normal saline group than in...

Effects of Hypertonic Saline (7.5%) on Haemodynamics and Extracellular Water Volumes after Coronary Artery Bypass Grafting and before Spinal Anaesthesia

COMPARISON BETWEEN THE EFFECTS OF 5 PERCENT HYPERTONIC SODIUM CHLORIDE SOLUTION AND 0.9 PERCENT SODIUM CHLORIDE SOLUTION ON LEFT VENTRICUL AR CONTRACTION

Hypertonic saline solution can absorb part of the intracellular fluid volume into the extracellular space. The effects of this solution on the cardiovascular system are increased coronary flow and increased left ventricular contraction, without sympathetic system activation. This study was designed to assess the effects of hypertonic saline solution in open heart surgery and to compare it w...

Resuscitation of intraoperative hypovolemia: a comparison of normal saline and hyperosmotic/hyperoncotic solutions in swine.

BACKGROUND AND METHODS We compared a hypertonic saline-dextran solution (7.5% NaCl/6% dextran-70) with 0.9% NaCl (normal saline) for treatment of intraoperative hypovolemia. Fourteen anesthetized pigs (mean weight 36.3 +/- 2.1 kg) underwent thoracotomy, followed by hemorrhage for 1 hr to reduce mean arterial pressure to 45 mm Hg. A continuous infusion of either solution was then initiated and t...